蒂姆·基南

教育

• PhD: Materials Science & 工程 Alfred University, 2016
• MS:材料科学 & 工程 Alfred University, 2012
• BS: Biomedical Materials 工程 & Science Alfred University, 2010

传记

Dr. 基南研究玻璃, 陶瓷, 聚合物, and composite materials, and designs these materials to elicit therapeutic effects upon implantation in live tissue.

Prior work included thorough characterization of a gallium-containing bioactive silicate glass series, along with in vitro biological evaluation of these glasses against fibroblast, 成骨细胞, 骨肉瘤, 骨髓瘤细胞, and bacterial and fungal testing. Additional prior work included the development of composites of 聚合物 hydrogels and bioactive glass particles for delivery of therapeutic ions, and these materials were also evaluated through in vitro cell viability analysis and bacterial and fungal testing, demonstrating great potential for in situ anti-fungal properties.

Current work is focused on the inclusion of phosphorous and other constituents into these glasses and composites, in an attempt to increase the rate and efficacy of in vitro hydroxyapatite deposition while enhancing their anti-bacterial and anti-fungal properties. 另外, work is being conducted to synthesize the bioactive glass compositions described in the international standard ISO 23317, and conduct concurrent studies with these glasses for comparison against the experimental glass compositions.

A second topical area is the development of more rigid, 由天然, functionalized 聚合物s for use as scaffold and sealant materials in bone void-filling applications. Additional areas of interest include the functionalization of structural 陶瓷 surfaces for improved adhesion of 聚合物ic coatings, and additive manufacturing (3-D printing) of 陶瓷/glass/聚合物 composites for biomedical applications.

课程

• ENGR 115: Explorations in Materials Science
• CEMS 214:结构 & Properties of Materials
• CEMS 468: Biomedical Materials
• CEMS 568: Biomedical Materials (研究生 Course)

研究, 出版物, & 演讲

研究 & 出版物

• 基南T.J.普拉塞克·L.M.M厅.M.和鹪鹩.W., “Anti-Bacterial and Anti-Fungal Potential of Ga-Bioactive Glass and Ga-Bioactive Glass/Polymeric Hydrogel Composites” Journal of Biomedical Materials 研究 Part B: Applied Biomaterials, 105(5), p.1102-1113 (2017).
• 基南T.J.普拉塞克·L.M.考夫兰.M厅.M.鹪鹩A.W., “Structural 描述 and Anti-Cancerous Potential of Ga-Bioactive Glass/Polymeric Hydrogel Composites” Carbohydrate Polymers, 153, p. 482-491 (2016).
• 基南T.J.普拉塞克·L.M.基南·N.L.M厅.M.和鹪鹩.W., “合成, 描述, and in vitro Cytocompatibility of Ga-Bioactive Glass/Polymeric Hydrogel Composites” Journal of Biomaterials Applications, 31(4), p.553-67 (2016).
• 基南T.J.普拉塞克·L.M.麦金蒂·T.L.——托勒·M.R.M厅.M.和鹪鹩.W., “Relating Ion Release and pH to in vitro Cell Viability for Gallium-Inclusive Bioactive Glasses”, Journal of Materials Science, 51(2), p. 1107-1120 (2016).
• Placek L.M.基南·T.J.F先生.考夫兰.和鹪鹩.W., “描述 of Y2O3 and CeO2 Doped SiO2-SrO-Na2O Glasses”, Journal of Biomedical Glasses, 1, p.159-172 (2015).
• Placek L.M.基南·T.J.，李毅.;;;.普拉丹·D.博伊德·D.梅洛特N.P.和鹪鹩.W., “Investigating the Effect of TiO2 on the Structure and Biocompatibility of Bioactive Glass”, Journal of Biomedical Materials 研究 Part B: Applied Biomaterials (2015).
• 雷恩一.W.，哈桑扎德P.普拉塞克·L.M.基南·T.J.考夫兰.——布蒂尔·L.R.和托勒M.R., “Silver Nanoparticle Coated Bioactive Glasses – Composites with Dex/CMC Hydrogels: 描述, 溶解度, and In Vitro Biological Studies”, Macromolecular Bioscience, 15(3), p.1146-1158 (2015).
• Alhalawani一.M.F.——罗德里格斯.柯伦·D.J.， Co。.，基尔南S.， Arshad S.基南·T.J.鹪鹩A.W.克拉斯托·G.皮尔·S.A.F.和托勒M.R., “A Glass Polyalkenoate Cement Carrier For Bone Morphogenetic Proteins”, Journal of Materials Science: Materials in Medicine, 26(3), p. 1-9 (2015).
• 雷恩一.W.基南·T.考夫兰.F先生.R.博伊德·D.——托勒·M.R.，以及M厅.M., “Characterisation of Ga2O3-Na2O-CaO-ZnO-SiO2 Bioactive Glasses”, Journal of Materials Science, 48(11), p.3999-4007 (2013).
• Kucko N.W.基南·T.考夫兰.，以及M厅.M., “Fill Volume as an Indicator of Surface Heterogeneity in Glass Vials For Parenteral Packaging”, Journal of Pharmaceutical Sciences, 102(6), p.1690-1695 (2013).

Professional Experience

U.S. Provisional Patent Application No. 62/412,299, “Devitrification Resistant Compositions”, Filed on: 10/25/2016 by Conax Technologies LLC. 共同发明人:T.J. 基南L.M. 普莱塞克和M. M. 大厅.

U.S. Provisional Patent Application No. 62/364,711, “Devitrification Resistant Coating Compositions”, Filed on: 7/20/2016 by Conax Technologies LLC. 共同发明人:T.J. 基南L.M. 普莱塞克和M.M. 大厅.